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Professor Carreira's research program focuses on the asymmetric synthesis of biologically active, stereochemically complex, natural products. Target molecules are selected which pose unique challenges in asymmetric bond construction. A complex multistep synthesis endeavor provides a goal-oriented setting within which to engage in reaction innovation and design. Drawing from the areas of organometallic chemistry, coordination chemistry, and molecular recognition, Carreira's group is developing catalytic and stoichiometric reagents for asymmetric stereocontrol.

Carreira Group Ticino 2019
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Check out these recent publications from the Carreira lab:

M. Brandstätter, N. Huwyler, E.M. Carreira, Chem. Sci.凯时kb88集团网址在线官网, Advanced Article. Gold(I)-catalyzed stereoselective cyclization of 1,3-enyne aldehydes by a 1,3-acyloxy migration/Nazarov cyclization/aldol addition cascade.凯时kb88集团网址app检测

T. Sandmeier, F.W. Goetzke, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc.凯时kb88集团网址在线官网, 141凯时kb88集团网址安卓二维码 Iridium-Catalyzed Enantioselective Allylic Substitution with Aqueous Solutions of Nucleophiles.凯时kb88集团网址客户端登录

凯时kb88集团网址app检测凯时kb88集团网址地址官网S.L. Rössler, D.A. Petrone, E.M. Carreira, Acc. Chem. Res.凯时kb88集团网址首页下载, asap. Iridium-Catalyzed Asymmetric Synthesis of Functionally Rich Molecules Enabled by (Phosphoramidite,Olefin) Ligands.凯时kb88集团网址app检测

P. Sondermann, E.M. Carreira, J. Am. Chem. Soc.,凯时kb88集团网址app检测, 141凯时kb88集团网址软件地址 Stereochemical Revision, Total Synthesis, and Solution State Conformation of the Complex Chlorosulfolipid Mytilipin B.凯时kb88集团网址娱乐软件

Y. Sempere, J.L. Alfke, S.L. Rössler, E.M. Carreira, Angew. Chem. Int. Ed.,凯时kb88集团网址安卓二维码, 58凯时kb88集团网址线路平台Morpholine Ketene Aminal as Amide Enolate Surrogate in Iridium‐Catalyzed Asymmetric Allylic Alkylation.凯时kb88集团网址地址官网

凯时kb88集团网址安卓二维码B.S. Schreib, E.M. Carreira, J. Am. Chem. Soc., 凯时kb88集团网址软件地址, 141凯时kb88集团网址检测app. Palladium-Catalyzed Regioselective C−H Iodination of Unactivated Alkenes.凯时kb88集团网址线路平台

M. Isomura, D.A. Petrone, E.M. Carreira, J. Am. Chem. Soc., 凯时kb88集团网址线路官方, 141, 4738–4748. Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols.凯时kb88集团网址安卓登录

M. Brandstätter, M. Freis, N. Huwyler, E.M. Carreira, Angew. Chem. Int. Ed., 凯时kb88集团网址首页下载, 58, 2490–2494Total Synthesis of (–)‐Merochlorin A.凯时kb88集团网址客户端登录

S.L. Rössler, B.J. Jelier, P.F. Tripet, A. Shemet, G. Jeschke, A. Togni, E.M. Carreira, Angew. Chem. Int. Ed. 凯时kb88集团网址线路平台, 131, 536 –541. Pyridyl Radical Cation for C–H Amination of Arenes凯时kb88集团网址ios登录.

J. Boshkow, T. Scattolin, F. Schoenebeck, E.M. Carreira, Helv. Chim. Acta 凯时kb88集团网址客户端登录, 101, e18001. [1,3]‐Sigmatropic Shift of an Allylic Chloride.凯时kb88集团网址客户端登录

M.J.R. Richter, M. Schneider, M. Brandstätter, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc., 凯时kb88集团网址检测app, 140, 16704–16710. Total Synthesis of (–)-Mitrephorone A.凯时kb88集团网址手机软件

A. Chicca, M.A. Schafroth, I. Reynoso-Moreno, R. Erni, V. Petrucci, E.M. Carreira, J. Gertsch, Sci. Adv. 凯时kb88集团网址手机软件, 4, 1–10. Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high.凯时kb88集团网址客户端代理

J.F. Teiber, J. Xiao, G.L. Kramer, S. Ogawa, C. Ebner, H. Wolleb, E.M. Carreira, D.M. Shih, R.W. Haley, Biochem. Biophys. Res. 凯时kb88集团网址地址官网, 505, 87–92. Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates.凯时kb88集团网址客户端代理

A.G. Kravina, E.M. Carreira, Angew. Chem. Int. Ed. 凯时kb88集团网址线路官方, 57, 13159–13162. Total Synthesis of Epicolactone.凯时kb88集团网址ios登录

N.Hauser, P. Kraft, E.M. Carreira, Synthesis 凯时kb88集团网址线路平台, 50,4490–4500. Unconventional Rose Odorants: Serendipitous Discovery and Unique Olfactory Properties of 2,2-Bis(prenyl)-3-oxobutyronitrile and Its Derivatives.凯时kb88集团网址客户端代理

Y. Sempere, E.M. Carreira, Angew. Chem. Int. Ed., 凯时kb88集团网址安卓登录, 57, 7654–7658. Trimethyl Orthoacetate and Ethylene Glycol Mono-Vinyl Ether as Enolate Surrogates in Enantioselective Iridium-Catalyzed Allylation.凯时kb88集团网址在线官网

H. Wolleb, S. Ogawa, M. Schneider, A. Shemet, J. Muri, M. Kopf, E.M. Carreira, Org. Lett., 凯时kb88集团网址手机软件20, 3014−3016. Synthesis and Structure–Activity Relationship Studies of Anti-Inflammatory Epoxyisoprostane Analogues.凯时kb88集团网址代理

N. Sobotzki, M.A. Schafroth, A. Rudnicka, A. Koetemann, F. Marty, S. Goetze, Y. Yamauchi, E.M. Carreira, B. Wollscheid, Nat. Comm. 凯时kb88集团网址代理, 9, 1519. HATRIC-based identification of receptors for orphan ligands.凯时kb88集团网址软件地址

N. Sievertsen, E.M. Carreira, Chimia 凯时kb88集团网址ios登录, 72, 44–47. Apoc Social: A Mobile Interactive and Social Learning Platform for Collaborative Solving of Advanced Problems in Organic Chemistry凯时kb88集团网址代理.

D.A. Petrone, M. Isomura, I. Franzoni, S.L. Rössler, E.M. Carreira, J. Am. Chem. Soc. 凯时kb88集团网址安卓登录, 140, 4697–4704. Allenylic Carbonates in Enantioselective Iridium-Catalyzed Alkylations.凯时kb88集团网址平台二维码

E.M. Carreira, J. Isr. Chem. 凯时kb88集团网址app检测, 59, 114–121. Natural Products Synthesis: A Personal Retrospective and Outlook.凯时kb88集团网址线路官方

M. Soethoudt, S.C. Stolze, M.V. Westphal, L. van Stralen, A. Martella, E.J. van Rooden, W. Guba, Z.V. Varga, H. Deng, S.I. van Kasteren, U. Grether, A.P. IJzerman, P. Pacher, E.M. Carreira, H.S. Overkleeft, A. Ioan-Facsinay, L.H. Heitman, M. van der Stelt, J. Am. Chem. Soc. 凯时kb88集团网址代理, 140, 6067–6075. Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.凯时kb88集团网址安卓二维码

L.J. Nannini, Suren J.Nemat, E.M. Carreira, Angew. Chem. Int. Ed., 凯时kb88集团网址客户端登录, 130, 831–834. Total Synthesis of (+)-Sarcophytin凯时kb88集团网址娱乐软件.

M.V. Westphal, M.A. Schafroth, R.C. Sarott, M.A. Imhof, C.P. Bold, P. Leippe, A. Dhopeshwarkar, J.M. Grandner, V. Katritch, K. Mackie, D. Trauner, E.M. Carreira, J.A. Frank, J. Am. Chem. Soc. 凯时kb88集团网址平台二维码, 139, 18206–18212. Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.凯时kb88集团网址注册平台

 

 
 
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